Depression
How is Depression Treated?
Antidepressants
What are Antidepressants?
Antidepressants are a class of drugs that help treat depression. In general, antidepressants are designed to enhance the transmission of neurotransmitters, especially serotonin and dopamine. The most commonly used antidepressants prescribed are SSRIs and SNRIs, which have less toxicity and improved safety compared to first-generation antidepressants.
SSRIS (SELECTIVE SEROTONIN REUPTAKE INHIBITORS)
SSRIs are effective in treating major depression. It works by blocking the reabsorption (reuptake) of serotonin into neurons. As a result, serotonin is made available to neurons so signals can be sent more efficiently.
Below is a list of common SSRI medications:
- Zoloft (sertraline) – has minimal side effects and creates a calming effect
- Prozac (fluoxetine)
- Celexa (citalopram)
- Lexapro (escitalopram)
- Pexeva (paroxetine)
- Paxil (paroxetine)
SNRIS (SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS)
SNRIs ease depression by blocking neurotransmitters that transmit information between neurons. SNRIs help relieve depression by blocking the serotonin and norepinephrine reuptake in the brain, making these neurotransmitters readily available for transmission between neurons.
Below is a list of common SNRI medications:
- Cymbalta (duloxetine)
- Pristiq (desvenlafaxine)
- Effexor (venlafaxine)